The Cockcroft-Gault Formula - Creatinine Clearance Estimation (By Using GFR)

The Cockcroft-Gault Formula - Creatinine Clearance Estimation
(By Using GFR)

INTRODUCTION

The formula gives the Glomerular Filtration Rate, in ml/hour. In other words, it estimates the rate at which plasma ultrafiltrate is produced by the kidneys.

This is a quick and dirty estimate, and gives a good estimate only when creatinine clearance is stable. If the creatinine concentration is rising, applying this formula would be highly inaccurate.

For most purposes, however, the Cockcroft-Gault formula is the most common formula used by physicians to estimate creatinine clearance, and thus Glomerular Filtration Rate (ml/min/1.73 m2).

THE FORMULA

The Cockcroft-Gault Formula is Used to calculate Creatinine Clearance.

MEN : GFR = (140 - age) x Weight (kg) / (72 x serum creatinine(mg/dl)) X 1

WOMEN : GFR = (140 - age) x Weight (kg) / (72 x serum creatinine(mg/dl)) X 0.85

OR

MEN : GFR = (140 - age) x Weight (kg) / (72 x serum creatinine/88.6(mcmol/L)) X 1

WOMEN : GFR = (140 - age) x Weight (kg) / (72 x serum creatinine/88.6(mcmol/L)) X 0.85

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